重井医学研究所

研究業績Publication

分子遺伝部門  Division of Molecular Genetics


Successful production of genome-edited rats by the rGONAD method.
Kobayashi T*, Namba M*, Koyano T*, Fukushima M, Sato M, Ohtsuka M, Matsuyama M. (*equal contribution)
BMC Biotechnol. In press.
PubMed


i-GONAD: a robust method for in situ germline genome engineering using CRISPR nucleases.
Ohtsuka M, Sato M, Miura H, Takabayashi S, Matsuyama M, Koyano T, Arifin N, Nakamura S, Wada K, Gurumurthy CB.
Genome Biol. (2018) Feb 26;19(1):25. doi: 10.1186/s13059-018-1400-x.
PubMed


Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus.
Mii Y, Yamamoto T, Takada R, Mizumoto S, Matsuyama M, Yamada S, Takada S, Taira M.
Nat Commun. (2017) Dec 7;8(1):1973.
PubMed

Monoclonal Suncus Antibodies: Generation of Fusion Partners to Produce Suncus-Suncus Hybridomas.
Sado Y, Inoue S, Tomono Y, Matsuyama M, Fukushima M, Oohashi T, Jogahara T, Oda SI.
Acta Histochem Cytochem. 2017 Apr 27;50(2):71-84.
PubMed

Insufficiency of phosphatidylethanolamine N-methyltransferase is risk for lean non-alcoholic steatohepatitis.
Nakatsuka A, Matsuyama M, Yamaguchi S, Katayama A, Eguchi J, Murakami K, Teshigawara S, Ogawa D, Wada N, Yasunaka T, Ikeda F, Takaki A, Watanabe E, Wada J.
Sci Rep. (2016) Feb 17;6:21721. doi: 10.1038/srep21721.
PubMed

Cytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice.
Tanaka H, Goto H, Inoko A, Makihara H, Enomoto A, Horimoto K, Matsuyama M, Kurita K, Izawa I, Inagaki M.
J Biol Chem. (2015) May 22;290(21):12984-12998. (巻頭表紙)
PubMed

Secreted Frizzled-related Protein 1 (Sfrp1) Regulates the Progression of Renal Fibrosis in a Mouse Model of Obstructive Nephropathy.
Matsuyama M, Nomori A, Nakakuni K, Shimono A, Fukushima M.
J Biol Chem. (2014) Nov 7;289(45):31526-33.
PubMed

Defect of Mitotic Vimentin Phosphorylation Causes Microophthalmia and Cataract via Aneuploidy and Senescence in Lens Epithelial Cells.
Matsuyama M, Tanaka H, Inoko A, Goto H, Yonemura S, Kobori K, Hayashi Y, Kondo E, Itohara S, Izawa I, Inagaki M.
J Biol Chem. (2013) Dec 13;288(50):35626-35.
This paper is selected as a 'Paper of the Week'.
This paper is selected as a 'Recommended' paper by Faculty of 1000.

PubMed

Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells.
Inoko A*, Matsuyama M*, Goto H, Ohmuro-Matsuyama Y, Hayashi Y, Enomoto M, Ibi M, Urano T, Yonemura S, Kiyono T, Izawa I, Inagaki M.(*equal contribution)
J Cell Biol. (2012) Apr 30;197(3):391-405.
This paper is selected as a 'Recommended' paper by Faculty of 1000.(巻頭表紙)
PubMed

P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation.
Li P, Goto H, Kasahara K, Matsuyama M, Wang Z, Yatabe Y, Kiyono T, Inagaki M.
Mol Biol Cell. (2012) Apr;23(8):1582-92.
PubMed

The embryonic mouse gut tube as a model for analysis of epithelial polarity.
Matsuyama M, Shimono A.
Methods Mol Biol. (2012) 839:229-37.
PubMed

Nuclear Chk1 prevents premature mitotic entry.
Matsuyama M*, Goto H*, Kasahara K*, Kawakami Y, Nakanishi M, Kiyono T, Goshima N, Inagaki M. (*equal contribution)
J Cell Sci. (2011) Jul 1;124(Pt 13):2113-9.
PubMed

Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.
Ibi M, Zou P, Inoko A, Shiromizu T, Matsuyama M, Hayashi Y, Enomoto M, Mori D, Hirotsune S, Kiyono T, Tsukita S, Goto H, Inagaki M.
J Cell Sci. (2011) Mar 15;124(Pt 6):857-64.
PubMed

Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium.
Matsuyama M, Aizawa S, Shimono A.
PLoS Genet. (2009) Mar;5(3):e1000427.
PubMed

Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse.
Satoh W, Matsuyama M, Takemura H, Aizawa S, Shimono A.
Genesis.( 2008) Feb;46(2):92-103.
This paper is selected as a 'Recommended' paper by Faculty of 1000.(巻頭表紙)
PubMed

Liver receptor homologue-1 (LRH-1) activates the promoter of brain aromatase (cyp19a2) in a teleost fish, the medaka, Oryzias latipes.
Ohmuro-Matsuyama Y, Okubo K, Matsuda M, Ijiri S, Wang D, Guan G, Suzuki T, Matsuyama M, Morohashi K, Nagahama Y.
Mol Reprod Dev. (2007) Sep;74(9):1065-71.
PubMed

A novel isoform of Vinexin, Vinexinγ, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad.
Matsuyama M, Mizusaki H, Shimono A, Mukai T, Okumura K, Abe K, Shimada K, Morohashi K.
Genes Cells. (2005) May;10(5):421-34.
PubMed